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Levamisole, sold under the trade name Ergamisol among others, is a medication used to treat parasitic worm infections.Specifically it is used for ascariasis and hookworm infections.
|Product name||Levamisole hydrochloride||Identification No.||1B100446W|
|Product Batch No.||LV10466||Product date||2017/9/3|
|Batch size||500kg||Report date||2017/9/3|
|Specification||25kg／drum||Expiry date||4 years|
|CERTIFICATE OF ANALYSIS|
|Characters||A white or almost white crystalline power.||A white crystalline power.|
|Identification||It complies with the test for specific optical rotation.||Qualified|
|gives reaction of chlorides|
|Appearance of solution||Meets the requirements||Qualified|
|Specific optical rotation||﹣121°～﹣128°||-122.62°|
|Related substances||Each of impurities A, B, C, D, E≤0.2%||A:0.00%, B:0.00% ,C:0.04%, D:0.00%, E:0.01%|
|Any other impurity ≤0.1%||＜0.1%|
|Loss on drying||≤0.5%||0.10%|
|CONCLUSION||The product complies to the standard of BP2010,EP6.4.|
Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator. It is an anthelmintic (anti-worm) agent commonly used in large livestock such as cattle, pigs and sheep. Levamisole HCl is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans. Another interesting use of levamisole in humans is as a treatment for common warts (verruca vulgaris).
|Quinine Sulfate Dihydrate||6119-70-6|
The original synthesis at Janssen Pharmaceutica resulted in the preparation of a racemic mixture of two enantiomers, whose hydrochloride salt was reported to have a melting point of 264–265 °C; the free base of the racemate has a melting point of 87–89 °C. The racemic mixture is referred to as "tetramisole" - levamisole refers only to the levorotatory enantiomer of tetramisole.