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High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen

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High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen

China High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen supplier
High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen supplier High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen supplier

Large Image :  High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen

Product Details:

Place of Origin: China
Brand Name: wumeitech
Certification: ISO 9001
Model Number: 54965-24-1

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiable
Packaging Details: disguised packing/as required
Delivery Time: 3-7 days
Payment Terms: T/T, Western Union, Money Gram, Bitcoin, Bank transfer
Supply Ability: 800kg/month
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Detailed Product Description
CAS No: 54965-24-1 Assay: 99%
Molecular Weight: 563.64 Molecular Formula: C32H37NO8
Appearance: White To Off-white Powder Payment Terms: T/T, Western Union, Money Gram, Bitcoin, Bank Transfer
Sample: Yes Price: Negotiable

Basic Info:
Product Name:Tamoxifen Citrate (Nolvadex )
Synonyms:1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate;(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethanamine,citrate(1:;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethylaminecitrate(;2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin2-hydrox;ici46,474;kessar;noltam;tamofen
CAS:54965-24-1
MF: C32H37NO8
MW:563.64
EINECS: 259-415-2
MP:140-144 °c
Storage Temp. :2-8°C
Water Solubility:slightly soluble
Chemical Properties:white to off-white powder
Biological Activity:Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.
Uses :For the treatment of advanced and recurrent breast cancer and ovarian cancer, etc.
 
Clinical Application:
1). Treatment of breast cancer.
2). Prevention of breast cancer.
3). Anti-tumor and anti-multidrug resistance.
By reducing membrane negotiability and enhancing rigidity of inter-cell binding site, Tamoxifen citrate can reduce concentration and activity of cancer metastasis promoter and various activating enzymes, so as to inhibit or hinder growth and metastasis of cancer cell. In addition, it can promote cells surrounding tumor focus to secrete a negative growth factor - transforming growth factor TGF- G, inhibiting multiply indefinitely of cancer cells; inhibiting oxidative damage of DNA bases which is caused by hydrogen peroxide generated from human neutrophils. So except for breast cancer, it is good for treatment and prevention of other malignant neoplasms, and is used for treatment of brain tumors, liver cancer, prostate cancer, etc. In addition, Tamoxifen citrate can reduce release effect of membrane P170 glycoprotein through reducing membrane negotiability, improving intracellular effective concentration of cytotoxic drug and reducing drug resistance.
4). Heart protection.
 
Mechanism Of Action
TCT has cis-trans isomers, whose cis isomer shows a weak estrogenic effect, while the trans isomer has an anti-estrogenic effect. When early application of Tamoxifen or existence of low concentration, it binds to the estrogen receptor (ER) in cytoplasm, showing a weak estrogenic effect. After TCT entering into cell nucleus, it can inhibit transcription and synthesis of nuclear ER, generating a lasting anti-estrogen effect. The study found that many new features of TCT were related to the mechanism of action which was beyond its competitive estrogen receptors - membrane regulating mechanisms. TCT as the membrane modifier, can reduce cell circulation. On this basis, TCT can also serve as an antioxidant to protect cell membranes and human LDL from happening oxidative damage.
 

Product nameTamoxifen citrate (Nolvadex)
AppearanceWhite crystalline powder
IdentificationIR, UV conformConform
Loss on drying≤ 0.5ml0.21ml
Residue on ignitionNot more than 0.2%0.06ml
IronNot more than 0.005%0.0018%
Heavy metalsNot more than 0.001%0.0006%
Related substancesTotal: Not more than 1.0%
Individual: Not more than 0.5%
0.32%
0.14%
E-isomerNot more than 0.3%0.19%
Organic volatile impuritiesConformsConforms
Assay99.0~101.0%99.51%

 
Product list:

Testosterone BaseBoldenone BaseMGF
Testosterone AcetateBoldenone AcetatePEG MGF
Testosterone CypionateEquipoiseCJC-1295
Testosterone DecanoateBoldenone PropionateCJC-1295 DAC
Testosterone EnanthateBoldenone CypionatePT-141
Testosterone IsocaproateNandrolone BaseMelanotan-1
Testosterone PhenylpropionateNandrolone DecanoateMelanotan-2
Testosterone PropionateNandrolone phenylpropGHRP-2
Testosterone UndecanoateNandrolone undecylateGHRP-6
MethyltestosteroneNandrolone cypionateIpamorelin
FormestaneNandrolone propionateHexarelin
Oral TurinabolTiboloneSermorelin
Clostebol AcetateTrenbolone BaseOxytocin
FluoxymesteroneTrenbolone AcetateTB500
Testosterone Sustanon 250Trenbolone EnanthateHGH 176-191
MestanoloneMethyltrienoloneTriptorelin
StanoloneTrenbolone HexaTesamorelin
Mesterolone7-keto DHEAGonadorelin
Methenolone EnanthateDHEADSIP
Methenolone AcetateOxymetholone / AnadrolSelank
MethyldrostanoloneOxandrolone / AnavarBPC 157
Drostanolone PropionateStanozolol / WinstrolEpitalon
Drostanolone EnanthateMethandienone / DianabolFollistatin 344
Tamoxifen CitrateSildenafil citrateMK-2866
Clomifene citrateTadalafil / CialisAndarine / S4
Toremifene citrateVardenafilGW501516
ExemestaneAvanafilRAD140
Anastrozole SR9009
   
LetrozoleFinasterideYK11
AndrostadiendioneYohimbine HCLMK-677
AndrostenedioneEplerenoneLGD4033

 

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We are a reliable supplier of raw steroid in China area of many years.
Our products have exported to USA, Greece, Spain, UK, Australia etc.
We are a experienced partner to send the steroid safely.
So we hope to cooperate with you to realize mutual benefit and achieve success.
 
High Purity Tamoxifen Citrate Nolvadex SERMs Steroids Anti-breast cancer CAS 54965-24-1 Tamofen

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