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|Product Name::||Mifepristone||Appearance::||Colorless Or Light Yellow Liquid|
|CAS Number::||84371-65-3||Molecular Formula::||C29H35NO2|
|Molecular Weight::||429.65||Melting Point::||195-198 Degree C|
Mifepristone Raw Steroid Powder , Synthetic Anabolic Steroids 99.5% Purity CAS 84371-65-3
1: Quick Details:
Product Name: Mifepristone
Appearance: Colorless or light yellow liquid
CAS Number: 84371-65-3
Molecular Formula: C29H35NO2
Molecular Weight: 429.65
Melting Point: 195-198 Degree C
Use: Used for a variety of allergic skin diseases and cosmetic additives
Packing: 1kg/aluminum foil bag
2. Mifepristone Application:
Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing's Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing's syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.
3. Mifepristone Function:
Mifepristone plays a role on the receptor level of new antifertility drugs, no progesterone, androgen, estrogen activity. It has an effect on softening and dilating uterine neck. It is a new anti - progesterone, and anti-glucocorticoid activity, without progesterone, estrogen, androgen and estrogen activity. And progesterone receptor affinity is 5 times stronger than progesterone. For termination of early pregnancy, reinstating menstruation and terminating pregnancy, fetal death, etc. In induction of labor.
Mifepristone can also be used in smaller doses as an emergency contraceptive; If taken after sex but before ovulation, it can prevent ovulation and so prevent pregnancy. In this role, a 10-mg dose is not as effective as the 600-mg dose, but has fewer side effects. Mifeprex and Mifegyne are only available in 200-mg tablets.
A review of studies in humans found that the contraceptive effects of the 10-mg dose were probably due mainly to its effects on ovulation, and not inhibition of implantation, but "the knowledge of the mechanism of action remains incomplete". Treatment with 200 mg of mifepristone changes steroid receptor expression in the Fallopian tube, inhibits endometrial development, and effectively prevents implantation.
Other medical applications of mifepristone studied in clinical trials include regular long-term use as an oral contraceptive, and treatment of HIV infection, uterine fibroids, endometriosis, major depression with psychotic features, bipolar depression and disorders causing cognitive dysfunction, post-traumatic stress disorder, chronic multisymptom illness, glaucoma, meningiomas, breast cancer, ovarian cancer, and prostate cancer.
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's syndrome (due to ectopic/neoplastic ACTH/cortisol secretion).
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient.
4. Mifepristone Description:
Mifeprex is used, together with another medication called misoprostol, to end an early pregnancy. The FDA first approved Mifeprex in 2000. In 2016, the agency approved a supplemental application for Mifeprex based on data and information submitted by the drug manufacturer. After reviewing the supplemental application, the agency determined that Mifeprex is safe and effective when used to terminate a pregnancy in accordance with the revised labeling.
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's syndrome (due to ectopic/neoplastic ACTH/cortisol secretion). During early trials, it was known as RU-38486 or simply RU-486, its designation at the Roussel Uclaf company, which designed the drug. The drug was initially made available in France, and other countries then followed-often amid controversy. It is marketed under tradenames Korlym and Mifeprex, according to FDA Orange Book.
5. Our Advantage:
>> High quality with competitive price:
1) Standard: BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.
>> Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
And we have stock in there for transferring.
>> We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
6. Mifepristone COA:
|Description||Light Yellowish Crystalline Powder||Light Yellowish Crystalline Powder|
|Specific Rotation||+124°~ +129°||+127.1°|
|(HPLC) Related substances||(1)(Single): ≤0.5%||0.31%|
|Loss On Drying||≤0.5%||0.1%|
|Manufacturer||Zhuhai Wumei Technology Co., Ltd|
7. Our Service
A. Lead Time: Within 12hours after you payment
B. Delivery Time: 3-7 working days
C. Packing: Very discreet or as your requirement
D. Shipping: DHL / TNT / UPS / HKEMS / FedEx / etc.
E. Tracking number: The tracking number will give to you after goods send out at first time.
F. After-sales service: 24/7 online for you to solve problems.