Aicar Drug Cycling Inhibitor Acadesine 10mg Muscle Gaining 2627-69-2

Oral Finished Steroids Aicar Muscle Gaining Acadesine Increasing Muscle Endurance 10mg*100/bottle CasNO.2627-69-2

Quick Detail

Product Name	Aicar
Aicar CAS	2627-69-2
Aicar Molecular Formula	C9H14N4O5
Aicar Molecular Weight	258.23
Assay	99%
Molecular Structure
Grade	Pharmaceutical Grade
Delivery time	Within 24h after your payment
Packing	Discreet package for delivery guarantee
Delivery terms	EMS, HKEMS, FEDEX, DHL, UPS, Aramex, ETC
Payment	, Money gram, Bank Transfer, Bitcoin, Litecoin

Hjtc (Xiamen) Industry Co., Ltd.

Xiamen Huayongjian Biotechnology Co., Ltd.

Contacts: June & Eason

Whatsapp:+8618206063252; +8618759200098

E-mail: june@steroidpowder-hjtc.com;

eason@steroidpowder-hjtc.com

Web site:https://www.steroidpowder-hjtc.com/
http://www.safeststeroid.com/
http://www.glassviallabels.com/
https://hjtc-printing.en.made-in-china.com/

Specification

Description

AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in, but there are some amazing side effects.

Interestingly, AICAR has been shown to protect against ischemic injury. This type of injury is directly related to the restriction of blood to tissues, which can cause insufficient amounts of oxygen and glucose needed to keep the tissue alive. This can lead to thrombosis, embolisms, and vasoconstriction. AICAR can be used as a stabilizing peptide for ischemic episodes, and it can allow for proper blood flow to the myocardium (heart). This function is very interesting, as AICAR could be fundamentally used to treat the heart muscle in the aftermath of a heart attack. This might reduce the possibility for ischemic injuries. Abnormal growths of heart tissues and heart valve function have also been altered in animal studies that used the peptide AICAR, which is a downside.

Dosage

Dosages range from 150 milligrams (mg) per day (if stacked with GW), up to 500mg a day when used solo. Considering the fact that each bottle typically comes in 50mg dosages, that is quite expensive, as already mentioned above. Economically, it makes most sense to run AICAR during the 4 weeks leading up to your competition.

Function

AICAR strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK, and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).

AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase. AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.

Competitive Advantage:

1. Best prices with satisfied quality;

2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS);

3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

4.Specials are possible when client's order is big enough, including the discount policy;

5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;

6.We can help our regular clients to suggest some vials factories which produce different size vials(2ml, 5ml, 7ml, 10ml, 20ml...), hoping can bring you convenience if you need these vials too.

How to proceed order:

First: Please let me know the items you are looking for, quantity, and the destination country.

Second: You confirm all details, and offer us purchasing order;

Third: We send the detail price of our product and offer the suitable shipping method for reference.

Fourth: You confirm the order and pay money 100% in advance and send us the detailed address.

Fifth: We arrange the shipment according to your requirements.

Sixth: We offer after-sales service after you receive parcel

Packaging & Delivery

1. Fastest delivery. We will deliver the products in 12 hours when we receive the payment.

2. Good delivery company. We use the legal delivery company so you can receive the product for sure.

3. Good package. Unique ways to ship 10grams to 100kg powders at one time to your destination. Fast and discreet shipment will be arranged for customs to pass Customs.

4. Professional team. Packing pictures and tacking code will be sent to you within 12 hours after receiving the payment. Updated tracking information will be provided every other day.

After Sales Service

1. We will ship the goods within 8hrs after get your payments. If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.

2.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.

3. you can get the goods with in 4-7days usually.If the goods were lost or not received for other reasons, please contact me Immediately.

Frequently Asked Question

Q1:How to confirm the Product Quality before placing orders?
A:free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

Q2:Can you give me a discount price?
A:Surely,It depend on your qty.Larger order can enjoy cheaper price.

Q3:When you ship my order?
A:Normally within 2 to 3 days after confirming your payment,because we need time to arrange Stealth Packing for 100% customs clearance.

Q4:Can you guarantee I can get my goods without any custom problem?
Yes, We have Reship Service.You can get your goods without any problem.

Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss.

Q6:Which kind of payment terms do you accept?
A:For any order,you can pay by Paypal,Bitcoin,T/T,Western Union or Money Gram.

Q7: How to contact with us?
A:We use email, whatsapp, wickr me, wechat,ect. so pls be free to contact me if you have any needs.